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111SKIN is the culmination of twenty years of surgical knowledge, innovative ingredients and medically-inspired delivery methods; founded by globally renowned Harley Street cosmetic surgeon Dr. Yannis Alexandrides, the original formula was developed to help his patients’ skin heal after trauma and given complimentary after treatments for more effective results and improved healing time.


Dr. Yannis Alexandrides is an American and European board-certified plastic surgeon specializing in facial reconstruction and rejuvenation surgery. A pioneer in aesthetic treatments, Dr. Yannis was among the first surgeons to advocate non-surgical procedures, and since 2001 he has been the founder, director and head of surgical practice at renowned 111 Harley St. Fulfilling a need to encourage recovery in his post-treatment patients, Dr Yannis developed an inaugural healing serum. From there, 111SKIN was born.

After completing her masters degree in the US, Eva Alexandridis moved to London with her husband and two sons. Recognizing the efficacy of her husband's product, Eva took 111SKIN to the retail market. Now spearheading the creative direction and new product development arm of 111SKIN, Eva regularly travels the world to seek new innovations and ingredients, growing the initial serum to 6 ranges and over 50 products.

Eva also focuses on growing the ethical and philanthropic aspects of the company, currently increasing the brands sustainability in packaging and practice. Due to her philanthropic efforts, 111SKIN was awarded the Positive Luxury Butterfly logo, which recognizes brands in the luxury sector that are dedicated to sustainability, ethics and conscious consumerism. 111SKIN proudly supports Women for Women International, a charity which helps women survivors of war rebuild their lives. 111SKIN sponsor a sister through a year-long training programme, where she learns how to earn and save money, improve her family’s health and make her voice heard at home and in her community.

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111 Harley St., one of London’s most premier clinics, where he was one of the first surgeons to advocate the use of non-surgical procedures. Understanding the need for prevention - not intervention - Dr. Yannis treats his patients with a unique combination of clinical medicine and a holistic approach, achieving their desired goals with the least interventional methods possible.

111HarleySt Clinic

The Beginning

After inserting a pure-collagen sponge soaked in NAC under the skin of a surgical patient to accelerate healing, Dr Yannis elevated the formula for his non-surgical patients. From there, NAC Y2 was born, a complex that includes a trio of actives with superior antioxidant capabilities, one of which stimulates the production of Glutathione – the body’s most powerful intracellular antioxidant. The superior results included epidermal strengthening, scar reduction, supports the healthy production of collagen, hyaluronic acid and elastin in the skin, and a more youthful appearance overall.

Used as the core of every product in the Reparative range and included in several other ranges, NAC Y2 has come to embody the principal of 111SKIN - innovative science that yields unrivalled results. 


“We bring clinically-inspired skincare that addresses real-life concerns to our customers. Using my 20+ years of expertise and medical observations, we develop products using innovative formulas that are engineered using the most sophisticated methods for efficient penetration of the skin and the highest levels of efficacy. We strive to bring the best of Harley Street to your home, creating skincare that can replicate in-clinic treatments, all while feeling opulently indulgent and a sensorial pleasure.”


 -Dr. Yannis Alexandrides MD Founder of 111SKIN and renowned Plastic Surgeon.

Positioned in leading luxury spaces and an international presence that is coveted by fashion designers, make-up artists and supermodels alike, 111SKIN formulates its skincare to deliver a no filter confidence. They are located in some of the most prestigious retail spaces like Holt Renfrew and Saks Fifth Avenue. They also offer aesthetic performance face and body treatments with their revolutionary spa concept that is present in the world’s leading spa resorts and hotels like Elora Mill, 124Q, Four Seasons and Spa at the Old Mill.

The focus for the future is to continue to deliver unprecedented quality and results to clients and customers as well as positioning themselves as the leading global skincare brand that is surgically inspired, science led and drives clinical results.

Where 111SKIN is today


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